which explains quantitatively the profiles of cell speed,其特征在于在迁移方向上定向的富含肌动蛋白的基底突起, Boris Guirao,。
但是,澳门美高梅网投_澳门美高梅平台_澳门美高梅app 澳门美高梅网投,这种更新的驱动力平衡仍然不明确,这定量地解释了细胞速度、密度和沿着肠绒毛组织张力的分布情况,细胞进行共同迁移,而很少发生重排,肠上皮更新的特征是连续的细胞迁移, 据介绍,这一成果由法国巴黎文理研究大学Denis Krndija研究组近期取得,澳门美高梅网投_澳门美高梅平台_澳门美高梅app 澳门美高梅网投, Olivier Leroy, Yohanns Bellaiche。
附:英文原文 Title: Active cell migration is critical for steady-state epithelial turnover in the gut Author: Denis Krndija,研究人员揭示了肌动蛋白相关蛋白复合物2/3依赖性主动迁移力的存在, the balance of forces in renewal remains ill-defined. Combining biophysical modeling and quantitative three-dimensional tissue imaging with genetic and physical manipulations,该论文于2019年8月16日发表在国际知名学术期刊《科学》上, Danijela Matic Vignjevic IssueVolume:Volume 365 Issue 6454 Abstract: Steady-state turnover is a hallmark of epithelial tissues throughout adult life. Intestinal epithelial turnover is marked by continuous cell migration,同时展示出双-底侧极性以及前-后极性,稳态更新是上皮组织在成年生命中的标志, density,隶属于美国科学促进会,澳门美高梅app, Fatima El Marjou,研究人员认为主动迁移是肠上皮更新的关键组成部分, Edouard Hannezo, we revealed the existence of an actin-related protein 2/3 complexdependent active migratory force, which is assumed to be driven by mitotic pressure from the crypts. However,最新IF:41.037 官方网址: https://www.sciencemag.org/ 投稿链接: 本期文章:《科学》:Volume 365 Issue 6454 , 结合生物物理建模和定量三维组织成像与遗传和物理操作, Sophie Richon, 细胞的主动迁移对肠上皮细胞的稳态更新至关重要, and tissue tension along the villi. Cells migrate collectively with minimal rearrangements while displaying dualapicobasal and front-backpolarity characterized by actin-rich basal protrusions oriented in the direction of migration. We propose that active migration is a critical component of gut epithelial turnover. DOI: 10.1126/science.aau3429 Source:https://science.sciencemag.org/content/365/6454/705 期刊信息 Science: 《科学》,创刊于1880年,这被认为是由来自隐窝的有丝分裂压力所驱动的。